The COVID-19 pandemic has had devastating effects on virtually all facets of society. With the enforcement of COVID-19 control measures such as lockdown and stay-at-home orders in Nigeria, palpable concerns about human rights violations by state actors, especially the security agencies, emerged. Unfortunately, conceptualizing and structuring responses to the COVID-19 pandemic as a human rights issue has remained inadequate, and very little research exists on the possible effects of pandemic containment policies on the human rights of informal workers in Nigerian cities.